Resources - Stem Cell Research / Tissue Engineering
3D InsertTM , is a very powerful tool in conducting stem cell in vitro expansion,
differentiation, and tissue engineering researches. It has been demonstrated in
our experiment and in many scientific publications that stem cell growth and
differentiation can be significantly enhanced in 3D environment, such as in 3D
porous scaffolds (Please see references in Technical Resources, and 3D Biotek's
Experimental Data).
3D InsertTM for stem cell/tissue engineering research application is fabricated
from both biodegradable and non-biodegradable polymers, such as polycaprolactone
(PCL) and polystyrene (PS).
Polycaprolactone (PCL) is a biodegradable polymer which has been used in
fabrication of surgical implants. It has also been extensively studied as a
biodegradable scaffold material for tissue engineering applications (list of
references). PCL 3D InsertTM is biodegradable with various precisely controlled
porous structure to meet you needs (Please see Products & Services and shop at
our Online Store).
Polystyrene (PS)
is the polymer that is used in fabrication of various cell culture vessels, such
as tissue culture plates (TCP) and tissue culture flasks. They are non-cytotoxic
and crystal clear. Similarly, PS 3D InsertTM is
tissue culture surface treated and transparent. The transparence of the PS 3D
InsertTM is a huge advantage comparing to other
porous scaffolds because it makes it possible for researchers to directly
observe the cell growth under routine cell culture inverted microscope. This
means that 3D cell culture can be conducted very continently and economically
without the need of adding expensive instruments. It also means that all routine
2D cell culture protocols can be easily adapted to 3D cell culture with few
changes. PS 3D InsertTM is suitable for 3D stem
cell expansion and differentiaion. It can also be used as an excellent control
and co-culture device for biodegradable 3D InsertTM
Other types of
biodegradable 3D InsertTM, such as PLGA , PLA
3D InsertTM are currently under development and
will be available soon to meet your needs.