Products - 3D Cell Culture
2D vs 3D cell culture comparison
Currently, cells are routinely cultured in vitro using 2 dimensional (2D) cell
culture techniques. It has been well documented that cell culture in tissue
culture plates and flasks does not mimic the in vivo cell growth. Therefore, the
cell expansion and cell-drug interactions under 2D are not appropriate in vitro
models. 3D cell culture technique, on the other hand, offers a better cell
culture environment because it is one step closer to the in vivo cell growth
environment. However, because 2D culture is easy to carry out and there are no
satisfactory 3D cell culture devices available, 2D cell culture is still the
predominately used cell culture technique. As a publication in the journal
Nature pointed out, “Awareness of the potential of 3D tissue culture among
scientists is far too low. But the benefits of the technique are so self-evident
that little marketing will be needed to persuade the uninitiated to move up one
dimension, just as soon as the issues of convenience are resolved” [Nature, Vol.
424, 21, August 2003].
Having realized the importance of conducting cell culture
under 3D, 3D Biotek has been working on developing easy to use 3D cell culture
devices. The initial application of these 3D cell culture devices will be
primarily in the stem cell research, tissue engineering, and drug discovery and
will expand to other cell culture related fields gradually.