Resources - Stem Cell Research / Tissue Engineering


3D InsertTM , is a very powerful tool in conducting stem cell in vitro expansion, differentiation, and tissue engineering researches. It has been demonstrated in our experiment and in many scientific publications that stem cell growth and differentiation can be significantly enhanced in 3D environment, such as in 3D porous scaffolds (Please see references in Technical Resources, and 3D Biotek's Experimental Data).


3D InsertTM for stem cell/tissue engineering research application is fabricated from both biodegradable and non-biodegradable polymers, such as polycaprolactone (PCL) and polystyrene (PS).


Polycaprolactone (PCL) is a biodegradable polymer which has been used in fabrication of surgical implants. It has also been extensively studied as a biodegradable scaffold material for tissue engineering applications (list of references). PCL 3D InsertTM is biodegradable with various precisely controlled porous structure to meet you needs (Please see Products & Services and shop at our Online Store).


Polystyrene (PS) is the polymer that is used in fabrication of various cell culture vessels, such as tissue culture plates (TCP) and tissue culture flasks. They are non-cytotoxic and crystal clear. Similarly, PS 3D InsertTM is tissue culture surface treated and transparent. The transparence of the PS 3D InsertTM is a huge advantage comparing to other porous scaffolds because it makes it possible for researchers to directly observe the cell growth under routine cell culture inverted microscope. This means that 3D cell culture can be conducted very continently and economically without the need of adding expensive instruments. It also means that all routine 2D cell culture protocols can be easily adapted to 3D cell culture with few changes. PS 3D InsertTM is suitable for 3D stem cell expansion and differentiaion. It can also be used as an excellent control and co-culture device for biodegradable 3D InsertTM


Other types of biodegradable 3D InsertTM, such as PLGA , PLA 3D InsertTM are currently under development and will be available soon to meet your needs. 


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